Ethanol derived acetate modifies brain epigenetic landscape

Derek Sung: @immunofluorescence

Faculty Spotlight: Cesar de la Fuente

Regenerating the lung: harnessing the untapped potential of AT2 cells

Where are they now – Theonie Anastassiadis

Faculty Spotlight: Will Bailis

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March 1, 2018

Sensorineural hearing loss (SNHL) is a common sensory deficit, which affects 1 in 500 newborns, and can arise from etiologically diverse structural and functional inner ear abnormalities. The mammalian inner ear is an elegant labyrinth that contains a cochlea, the primary auditory organ, and a vestibular system that maintains body balance. Lateral cochlear duct cells, comprising Reissner’s membrane and the stria vascularis, are critical for production, maintenance and secretion of endolymph, a specialized fluid that supports hair cell function. A recent Developmental Cell paper by Alex Rohacek, a DSRB student from Douglas Epstein’s lab, highlights a compl...

May 20, 2017

The NSF-funded Center for Engineering Mechanobiology is a new science and technology center (STC) at Penn launched this past fall. STCs are integrative partnership programs between multiple labs and across multiple campuses that enable innovative research at the interface of biological and physical sciences. I met with Dr. Rebecca Wells, an associate professor of Medicine and education director for the Penn STC, to talk about the wealth of opportunities for cross-disciplinary research this new centerthat the Center for Engineering Mechanobiology brings to Penn.

What is the purpose for the Center of Engineering Mechanobiology?

The goal is to bring together...

February 14, 2017

You may have been actively trying to erase all traces of 2016 from your memory, but the CAMB Student Newsletter would like to remind you of the year that just zoomed by. During the annual CAMB holiday celebration this past December, we ambushed students, faculty, and program coordinators and asked them to reflect on their 2016 experiences. From getting married to fellow scientists to exploring space, from curing blindness in dogs to adopting kittens, ‘CAMBers’ had an action-packed year!

The previous year was a year of change and new beginnings for many of us. There were new people. Christina Strathearn joined the CAMB office as the fourth CAMB coordinator....

November 3, 2016

The University of Pennsylvania is a leader in chimeric antigen receptor (CAR) T cell research and in translating basic research findings into successful clinical trials. CAR T cell therapies are designed to attack and destroy cancer by harnessing a patient’s own immune system. Researchers extract the patient’s T cells, modify them outside of the body so that they recognize tumor cells, and reintroduce the modified T cells back into the patient’s blood. The goal of this therapy is to provide a safe, highly specific, and long-term anti-tumorigenic system to prevent cancer relapse. Unprecedented clinical responses to CD19-specific CAR T cell therapy in patie...

August 23, 2016

Crafting a non-academic career path for a typical CAMB graduate student can be a complex balancing act of juggling never-ending hours of lab work, hobbies, and a personal life. Meeting recent CAMB alumni who have successfully navigated the real-life labyrinths to secure non-academic jobs can thus be refreshing and inspiring. Renske Erion is a recent alumna of the Cancer Biology subgroup who completed her Ph.D. in Amita Sehgal’s lab, where she studied mechanisms of circadian rhythm regulation. She is currently a project director for the Emerging Leaders in Science and Society (ELISS) Program in Seattle, Washington.

The ELISS program is a service-oriented ex...

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