Ethanol derived acetate modifies brain epigenetic landscape

Derek Sung: @immunofluorescence

Faculty Spotlight: Cesar de la Fuente

Regenerating the lung: harnessing the untapped potential of AT2 cells

Where are they now – Theonie Anastassiadis

Faculty Spotlight: Will Bailis

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November 27, 2018

Since beginning graduate school, I have been a part of the Graduate Training in Medical Science (GTMS) Certificate Program. The GTMS program integrates focused medical education and experience into the doctoral curriculum, giving Ph.D. students insight into the integration of lab and clinic. Started in 2006 and funded by the Howard Hughes Medical Institute, the program was so successful that Penn decided to keep it going after the three-year pilot grant ended.

Directed by Dr. Hao Shen and Dr. Jonathan Katz, the rigorous program focuses on training basic scientists to have a clearer understanding of human biology and pathology through clinically relevant re...

August 27, 2017

Fat has a bad reputation for its negative contribution to a host of diseases such as cardiovascular disease, diabetes, and obesity. However, not all fat is created equally. The study of brown adipose tissue (BAT) is becoming a hot topic in the world of gene regulation, metabolic diseases, and in the exercise industry. Rising interest in brown adipose tissue research parallels the growing efforts to combat rising obesity rates in America. The exercise industry is interested in understanding BAT for weight loss and healthy lifestyle maintenance. BAT is a highly metabolically active tissue that converts food energy into heat, which subsequently regulates the...

May 20, 2017

Transcription factors mediate many essential processes. The role of transcription factors in mediating neuronal growth, function, and regeneration is not well known. It is particularly poorly understood how the development, branching, and regrowth of motor neurons are regulated. There is also little known about how transcription factors regulate dendrite (projections of neurons) and how this works in conjunction with axonal outgrowth and targeting.

Regulation of dendrite and axon positioning is necessary to define a neuron’s connections and is controlled by a combination of guidance receptors, adhesion molecules, and cytoskeletal regulators. The lab of Dr....

February 14, 2017

Is the “traditional postdoc” actually traditional?

Most graduate students who want to pursue the academic route aim to complete a “normal” postdoctoral fellowship in a basic research lab at a prestigious institution. CAMB alumnus Geoffrey Hannigan (GTV) is setting himself apart from others on this path by keeping “all his doors open.” Geof earned his Ph.D. in Dr. Elizabeth Grice’s lab, where he investigated viral communities on the skin in relation to wound healing and open fractures. After defending in 2015, he began his postdoctoral research at the University of Michigan in the lab of Dr. Pat Schloss. As a postdoc, Geof investigates the microbiome of the...

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