Ethanol derived acetate modifies brain epigenetic landscape

Derek Sung: @immunofluorescence

Faculty Spotlight: Cesar de la Fuente

Regenerating the lung: harnessing the untapped potential of AT2 cells

Where are they now – Theonie Anastassiadis

Faculty Spotlight: Will Bailis

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August 16, 2019

Dr. Rinho Kim started his Ph.D. in the Fall of 2010 as part of the Genetics and Epigenetics graduate group. He joined Dr. Klaus Kaestner’s lab for his thesis work in studying the epigenetic regulation of intestinal stem cell differentiation. Dr. Kim was always interested in Next-Generation Sequencing (NGS) technologies and started working on developing his wet and dry lab skills in the field early on in his thesis project.

After graduating in the fall of 2016, Dr. Kim wanted to apply his skills to human disease research. He also wanted to explore opportunities in Europe, having spent the previous 8.5 years in the US after moving here from South Korea. He t...

July 12, 2019

Although new cases of colorectal cancer (CRC) are on the decline, CRC is amongst the top four most commonly diagnosed cancers in the United States according to the latest NCI SEER report. Underlying risk factors such as smoking, obesity, and family genetic history can lead to malignant transformation of intestinal epithelial cells. At the molecular level, mutations in the genes APC, LKB1, MLH2, and MYH have been associated with colorectal tumor initiation or progression. However, regulation at the transcriptional-translational interface by RNA-binding proteins (RBPs) has not been well characterized within CRC. To clarify the role of the RBPs LIN28B and IM...

July 11, 2019

Over the last decade, DNA sequencing technologies have become more accessible, and a number of companies offering to unlock the secrets of our genome have become increasingly popular. These companies market themselves as tools for learning about ancestry and potentially connecting with distant relatives by analyzing their customers’ genomes. 

DNA extracted from saliva samples sent in by patrons is sequenced, and loci that are highly variable among different ethnic groups are compared to corresponding loci in existing libraries. The largest of these companies, Ancestry.com and 23&Me, have user libraries containing the genomes of over 15 million individuals...

July 10, 2019

Faculty from left to right (top photo): Dan Kessler, Chris Lengner, Joe Baur, Jean Bennett, Ben Prosser, Mary Mullins

March holds a beloved holiday for nerds all around the world: Pi Day. The classic way to celebrate this holiday is through feasting on pie, but here in CAMB we put a twist on this tradition. For the third year in a row, the CAMB Student Newsletter team hosted its annual “Pie a PI” event on Thursday, March 14. As the name suggests, this event involves gathering round and watching CAMB faculty members get pies thrown in their faces. In the days leading up to Pi Day, those wanting to pie a PI purchased $1 raffle tickets to enter for the chance...

July 3, 2019

Dr. Rachel Leibman graduated from CAMB (Microbiology, Virology, and Parasitology) in 2017 after completing her training in Dr. Jim Riley’s laboratory. After two years in her current position as a Clinical Scientist, she is excited to share her experience with current students, and tell us how CAMB graduates are undoubtedly qualified for this translational-focused field.

Rachel works for Stemcentrx, an oncology biotech startup acquired by AbbVie, a global pharmaceutical company and spin-off of Abbott Laboratories. As a Clinical Scientist, she supports clinical trials and clinical program development. Rachel describes herself as the right-hand woman to the M...

February 19, 2019

Malaria remains one of the world’s most devastating diseases. Campaigns to eradicate transmission have yielded encouraging results in recent years. However, expansion of vector habitats has resulted in substantial increases in disease burden in the Americas, South-East Asia, and Africa, with over 2 million new cases and 445,000 deaths reported in 2016.

While Plasmodium falciparum is responsible for most malaria cases in Africa, Plasmodium vivax is the leading cause of malaria elsewhere in the world, particularly in Southeast Asia and South America. P. vivax is thought to have originated as a human pathogen by zoonoses of ape parasites; the long-standing do...

February 19, 2019

Little League. High School Sports. NCAA College Athletics. The Super Bowl. The Olympic Games. Athletics are an important pillar throughout all stages of society. The Eagles are playing on everyone’s TV on most Sundays of the school year. Yet, student athletes seem to be forgotten in graduate school. Many CAMB students are still highly involved in athletics, from the social intramural level up through the professional level. These students have a passion competing in athletics that their fellow students and PIs alike are unaware of. This article spotlights four graduate student athletes, or “GRAthletes,” who participate in in a variety of sports to compete...

February 19, 2019

Creativity is, “the process of generating new information”, states Dr. Tina Seelig, professor at Stanford University and author on innovation entrepreneurship and creativity [1].

She continues to explain that, “[creativity] at the core is the ability to look at problems from different angles, to connect and combine concepts, and the ability to challenge traditional assumptions. These are skills that require practice to master.” Historically oversimplified as a property of the brain’s right-side hemisphere, creativity is a neurologically complex process involving the flow of mental connections across multiple brain networks [2,3]. This makes it clear that...

February 17, 2019

Not only is it cold and dark outside this winter, second years have an added worry, the start of prelims season. Prelims is a necessary part of every graduate student’s career, and arguably one of the most stressful experiences in graduate school. Any older graduate student will say that during the entire prelim process the exam was a source of constant stress. However, looking back on it, many students find that the exam itself was not terrible, and in some instances, even enjoyable. Although most preliminary exams are taken in May, there are a few reasons behind starting the preparation process at the being of February. The simplest and most important r...

November 27, 2018

“What do you want to do after graduate school?”

This is the question that every PhD student dreads hearing. There are so many career paths that students with a PhD can follow after graduating, and it can be quite overwhelming to chose which path to take. Fortunately, Career Services offers many resources that can help students choose a career. Dr. Joseph Barber, Senior Associate Director at Career Services for graduate students and postdocs, talks about the resources offered by Career Services and shares some tips for easing the process of deciding the next steps after graduate school.

The first thing to keep in mind is that it is never too early to go to C...

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