Ethanol derived acetate modifies brain epigenetic landscape

Derek Sung: @immunofluorescence

Faculty Spotlight: Cesar de la Fuente

Regenerating the lung: harnessing the untapped potential of AT2 cells

Where are they now – Theonie Anastassiadis

Faculty Spotlight: Will Bailis

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February 8, 2020

The physiological effects of alcohol on the brain and motor function have been studied extensively for decades. In low doses, alcohol causes euphoria and reduces anxiety, while in higher doses it impairs cognition and balance, and increases response time. Long-term consumption of alcohol is associated with changes in memory and alcohol-related learning, which play important roles in the development of alcohol use disorder. Dr. Philipp Mews, a CAMB graduate from the Genetics and Gene Regulation (now Genetics and Epigenetics) sub-program, explored the link between alcohol metabolism, gene expression, and alcohol-related learning behaviors, and recently publ...

April 26, 2016

The Cell and Molecular Biology (CAMB) program spans a daunting breadth of biological inquiry, with students and investigators participating across six dynamic and complementary programs. This diversity is exemplified by the research of Ellen Elliott, recent alumna of the Developmental, Stem Cell and Regenerative Biology (DSRB) program and the Kaestner laboratory. Her work integrates the methods and concepts of regenerative biology, organismal development, physiology, and epigenetic regulation to investigate the role of DNA methylation in mammalian intestinal epithelia. In the January 2016 issue of eLife, Ellen and colleagues present that the DNA methyltra...

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