Regenerating the lung: harnessing the untapped potential of AT2 cells

Where are they now – Theonie Anastassiadis

Faculty Spotlight: Will Bailis

Be The Match

GRAthletes in CAMB: Coral Kasden competes at 2019 Pan American Games in Lima, Peru

Greening Our Labs

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November 19, 2019

Runny noses, body aches, and chills – dreaded signs that the flu season is upon us. The cough, however, remains one of the most painful flu symptoms and is a clear indication that the influenza virus has successfully invaded the lungs. Though the lungs provide critical protection from environmental insults, they are also highly susceptible to injury caused by influenza. Fortunately, the lungs have a remarkable ability to regenerate in response to infection and disease. Damage to the lung often results in loss of alveolar type 1 (AT1) cells, which make up the majority of the lung epithelial surface and mediate oxygen and carbon dioxide gas exchange. Regene...

November 19, 2019

Dr. Theonie Anastassiadis, 2017 alumna of CAMB/Cancer Biology, thought she knew what she wanted to do after graduate school. Theonie always pictured herself on the academic track and eventually running her own lab. However, in the summer of 2017, Theonie pursued an opportunity that changed the course of her career by participating as a Summer Fellow at a biotechnology venture creation firm known as Flagship Pioneering in Cambridge, Mass. After her summer at the company, she was offered a full-time position, where she now works as part of an entrepreneurial team to originate, resource, manage and grow bioscience companies that create breakthroughs in healt...

November 19, 2019

I recently sat down with Dr. Will Bailis from the Department of Pathology and Laboratory Medicine. A relatively new faculty member and alum of our very own Immunology Graduate Group. I had a few questions that needed answering.

Q: Take me through your academic timeline

I grew up on the Mainline right outside of Philadelphia and attended Vassar College, where I was originally interested in studying history and foreign policy. Eventually, after not getting into some of the summer positions I wanted, I sent out tons of emails to labs at the major schools in Philadelphia and the only person to respond was Dr. Susan Ross at Penn. I ended up working in her lab fo...

November 19, 2019

A person is diagnosed with a blood cancer in the United States every 3 minutes. In 2019, blood cancer is expected to make up 10% of all new cancer cases diagnosed in the country. While chemotherapy remains the standard of care for blood cancer patients, hematopoietic stem cell transplant (also called bone marrow transplant) has improved the survival rate for some of these cancers from 0% to nearly 80%. Bone marrow transplant is a complex procedure where the patient’s damaged hematopoietic stem cells are completely removed with radiation and chemotherapy, and replaced with healthy stem cells from a matched bone marrow donor.

Be The Match is a national bone...

November 19, 2019

Coral Kasden, a second year GTV student, was featured as one of CAMB’s professional GRAthletes (“graduate athletes”) in the November 2018 issue of the CAMB Student Newsletter. Her goal last year was to be selected as coxswain for the United States boat in the 2019 Pan American Games in Lima, Peru. As an exciting update, she just accomplished this goal!

Coral is a rowing coxswain for the Men’s High Performance Group for the New York Athletic Club. Tucked into a small seat at the back of the boat, she steers, keeps the rowers on time, and directs the whole course of a race – an integral position that carries an immense amount of responsibility. Coral just ma...

August 16, 2019

In our personal lives, it is easy to list ways in which we can become “greener.” We can use reusable grocery bags, carry our own utensils and straws, hang our clothes out to dry, and so on. Although reducing our energy consumption and trash production is not always convenient, it is often relatively simple to implement these changes in our lives. As scientists, however, the path to being eco-friendly is less clear. We are all familiar with the piles of plastic and styrofoam we generate in our labs on a daily basis, but it can be easy to justify our waste or see it as inevitable. Elicia Preston, manager of the Murray Lab in the Department of Genetics at Pe...

August 16, 2019

Center City

  • Restaurants/Bars: 

    • Center City is a go-to for any type of food: quick bites at the crowded stalls in Reading Terminal Market, Philly classics like Federal Donuts, and special occasion establishments like Vernick Food and Drink.

    • Barbuzzo: Modern Mediterranean food. Save room for the salted-caramel budino dessert that can be spotted at almost every table.

    • Bob and Barbara’s: Local favorite with live jazz music on the weekends and the original home of the CityWide Special.

    • Parc: French Bistro and a Rittenhouse classic (also try the Caribou Cafe!).

    • Sampan/Graffiti Bar: Asian fusion cuisine. Follow the alle...

August 16, 2019

1st Year: Corey Holman

Welcome to Penn!!! I’m a first year CPM student in the Seale Lab who loves studying brown adipose tissue and metabolism. I took a couple years off to work as a tech before coming to Penn. Taking time off was the best decision for me - I got to discover what area of science really fascinated me, knew exactly which labs I wanted to rotate in, and gained life experience working for a couple years before going back to school. However, I have to say, the transition from working life back to school was difficult. I had never struggled in classes before but getting back into the studying mindset was harder than expected, especially in areas...

August 16, 2019

Dr. Rinho Kim started his Ph.D. in the Fall of 2010 as part of the Genetics and Epigenetics graduate group. He joined Dr. Klaus Kaestner’s lab for his thesis work in studying the epigenetic regulation of intestinal stem cell differentiation. Dr. Kim was always interested in Next-Generation Sequencing (NGS) technologies and started working on developing his wet and dry lab skills in the field early on in his thesis project.

After graduating in the fall of 2016, Dr. Kim wanted to apply his skills to human disease research. He also wanted to explore opportunities in Europe, having spent the previous 8.5 years in the US after moving here from South Korea. He t...

July 12, 2019

Although new cases of colorectal cancer (CRC) are on the decline, CRC is amongst the top four most commonly diagnosed cancers in the United States according to the latest NCI SEER report. Underlying risk factors such as smoking, obesity, and family genetic history can lead to malignant transformation of intestinal epithelial cells. At the molecular level, mutations in the genes APC, LKB1, MLH2, and MYH have been associated with colorectal tumor initiation or progression. However, regulation at the transcriptional-translational interface by RNA-binding proteins (RBPs) has not been well characterized within CRC. To clarify the role of the RBPs LIN28B and IM...

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