Ethanol derived acetate modifies brain epigenetic landscape

Derek Sung: @immunofluorescence

Faculty Spotlight: Cesar de la Fuente

Regenerating the lung: harnessing the untapped potential of AT2 cells

Where are they now – Theonie Anastassiadis

Faculty Spotlight: Will Bailis

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February 8, 2020

The physiological effects of alcohol on the brain and motor function have been studied extensively for decades. In low doses, alcohol causes euphoria and reduces anxiety, while in higher doses it impairs cognition and balance, and increases response time. Long-term consumption of alcohol is associated with changes in memory and alcohol-related learning, which play important roles in the development of alcohol use disorder. Dr. Philipp Mews, a CAMB graduate from the Genetics and Gene Regulation (now Genetics and Epigenetics) sub-program, explored the link between alcohol metabolism, gene expression, and alcohol-related learning behaviors, and recently publ...

February 8, 2020

Derek Sung, a third year CPM MD/PhD student in Mark Kahn’s lab, has found a unique way to showcase his appreciation for how beautiful cells can be - he runs the popular Instagram account, @Immunofluorescence. Derek utilizes immunofluorescence and confocal microscopy to study vascular biology and development during hematopoiesis, and in the placenta. He was first introduced to these techniques while working at the Laboratory of Molecular Cardiology at the National Heart, Lung, and Blood Institute at the NIH, and was particularly drawn to its inherent artistry. “Knowing the nuances in staining and imaging makes it as much of an art as a science,” he says. A...

February 8, 2020

I recently sat down with Cesar de la Fuente, a newly appointed Assistant Professor in the Departments of Microbiology, Psychiatry, and Bioengineering. Cesar leads a diverse group interested in using multiple approaches, including in-silico models and synthetic biology, to address global health challenges. Below is a paraphrased transcript of our discussion regarding his time at Penn, goals for the future, and advice for current trainees.

JG: Could you describe some of the projects in your lab

CF: Our main goal is to develop new molecular tools and medicines using computers. We are currently focusing on developing new antibiotics to help address the global h...

November 19, 2019

Runny noses, body aches, and chills – dreaded signs that the flu season is upon us. The cough, however, remains one of the most painful flu symptoms and is a clear indication that the influenza virus has successfully invaded the lungs. Though the lungs provide critical protection from environmental insults, they are also highly susceptible to injury caused by influenza. Fortunately, the lungs have a remarkable ability to regenerate in response to infection and disease. Damage to the lung often results in loss of alveolar type 1 (AT1) cells, which make up the majority of the lung epithelial surface and mediate oxygen and carbon dioxide gas exchange. Regene...

November 19, 2019

Dr. Theonie Anastassiadis, 2017 alumna of CAMB/Cancer Biology, thought she knew what she wanted to do after graduate school. Theonie always pictured herself on the academic track and eventually running her own lab. However, in the summer of 2017, Theonie pursued an opportunity that changed the course of her career by participating as a Summer Fellow at a biotechnology venture creation firm known as Flagship Pioneering in Cambridge, Mass. After her summer at the company, she was offered a full-time position, where she now works as part of an entrepreneurial team to originate, resource, manage and grow bioscience companies that create breakthroughs in healt...

November 19, 2019

I recently sat down with Dr. Will Bailis from the Department of Pathology and Laboratory Medicine. A relatively new faculty member and alum of our very own Immunology Graduate Group. I had a few questions that needed answering.

Q: Take me through your academic timeline

I grew up on the Mainline right outside of Philadelphia and attended Vassar College, where I was originally interested in studying history and foreign policy. Eventually, after not getting into some of the summer positions I wanted, I sent out tons of emails to labs at the major schools in Philadelphia and the only person to respond was Dr. Susan Ross at Penn. I ended up working in her lab fo...

November 19, 2019

A person is diagnosed with a blood cancer in the United States every 3 minutes. In 2019, blood cancer is expected to make up 10% of all new cancer cases diagnosed in the country. While chemotherapy remains the standard of care for blood cancer patients, hematopoietic stem cell transplant (also called bone marrow transplant) has improved the survival rate for some of these cancers from 0% to nearly 80%. Bone marrow transplant is a complex procedure where the patient’s damaged hematopoietic stem cells are completely removed with radiation and chemotherapy, and replaced with healthy stem cells from a matched bone marrow donor.

Be The Match is a national bone...

November 19, 2019

Coral Kasden, a second year GTV student, was featured as one of CAMB’s professional GRAthletes (“graduate athletes”) in the November 2018 issue of the CAMB Student Newsletter. Her goal last year was to be selected as coxswain for the United States boat in the 2019 Pan American Games in Lima, Peru. As an exciting update, she just accomplished this goal!

Coral is a rowing coxswain for the Men’s High Performance Group for the New York Athletic Club. Tucked into a small seat at the back of the boat, she steers, keeps the rowers on time, and directs the whole course of a race – an integral position that carries an immense amount of responsibility. Coral just ma...

August 16, 2019

In our personal lives, it is easy to list ways in which we can become “greener.” We can use reusable grocery bags, carry our own utensils and straws, hang our clothes out to dry, and so on. Although reducing our energy consumption and trash production is not always convenient, it is often relatively simple to implement these changes in our lives. As scientists, however, the path to being eco-friendly is less clear. We are all familiar with the piles of plastic and styrofoam we generate in our labs on a daily basis, but it can be easy to justify our waste or see it as inevitable. Elicia Preston, manager of the Murray Lab in the Department of Genetics at Pe...

August 16, 2019

Center City

  • Restaurants/Bars: 

    • Center City is a go-to for any type of food: quick bites at the crowded stalls in Reading Terminal Market, Philly classics like Federal Donuts, and special occasion establishments like Vernick Food and Drink.

    • Barbuzzo: Modern Mediterranean food. Save room for the salted-caramel budino dessert that can be spotted at almost every table.

    • Bob and Barbara’s: Local favorite with live jazz music on the weekends and the original home of the CityWide Special.

    • Parc: French Bistro and a Rittenhouse classic (also try the Caribou Cafe!).

    • Sampan/Graffiti Bar: Asian fusion cuisine. Follow the alle...

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