Ethanol derived acetate modifies brain epigenetic landscape

Derek Sung: @immunofluorescence

Faculty Spotlight: Cesar de la Fuente

Regenerating the lung: harnessing the untapped potential of AT2 cells

Where are they now – Theonie Anastassiadis

Faculty Spotlight: Will Bailis

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August 16, 2019

1st Year: Corey Holman

Welcome to Penn!!! I’m a first year CPM student in the Seale Lab who loves studying brown adipose tissue and metabolism. I took a couple years off to work as a tech before coming to Penn. Taking time off was the best decision for me - I got to discover what area of science really fascinated me, knew exactly which labs I wanted to rotate in, and gained life experience working for a couple years before going back to school. However, I have to say, the transition from working life back to school was difficult. I had never struggled in classes before but getting back into the studying mindset was harder than expected, especially in areas...

August 16, 2019

Dr. Rinho Kim started his Ph.D. in the Fall of 2010 as part of the Genetics and Epigenetics graduate group. He joined Dr. Klaus Kaestner’s lab for his thesis work in studying the epigenetic regulation of intestinal stem cell differentiation. Dr. Kim was always interested in Next-Generation Sequencing (NGS) technologies and started working on developing his wet and dry lab skills in the field early on in his thesis project.

After graduating in the fall of 2016, Dr. Kim wanted to apply his skills to human disease research. He also wanted to explore opportunities in Europe, having spent the previous 8.5 years in the US after moving here from South Korea. He t...

July 12, 2019

Although new cases of colorectal cancer (CRC) are on the decline, CRC is amongst the top four most commonly diagnosed cancers in the United States according to the latest NCI SEER report. Underlying risk factors such as smoking, obesity, and family genetic history can lead to malignant transformation of intestinal epithelial cells. At the molecular level, mutations in the genes APC, LKB1, MLH2, and MYH have been associated with colorectal tumor initiation or progression. However, regulation at the transcriptional-translational interface by RNA-binding proteins (RBPs) has not been well characterized within CRC. To clarify the role of the RBPs LIN28B and IM...

July 11, 2019

Over the last decade, DNA sequencing technologies have become more accessible, and a number of companies offering to unlock the secrets of our genome have become increasingly popular. These companies market themselves as tools for learning about ancestry and potentially connecting with distant relatives by analyzing their customers’ genomes. 

DNA extracted from saliva samples sent in by patrons is sequenced, and loci that are highly variable among different ethnic groups are compared to corresponding loci in existing libraries. The largest of these companies, Ancestry.com and 23&Me, have user libraries containing the genomes of over 15 million individuals...

July 10, 2019

Faculty from left to right (top photo): Dan Kessler, Chris Lengner, Joe Baur, Jean Bennett, Ben Prosser, Mary Mullins

March holds a beloved holiday for nerds all around the world: Pi Day. The classic way to celebrate this holiday is through feasting on pie, but here in CAMB we put a twist on this tradition. For the third year in a row, the CAMB Student Newsletter team hosted its annual “Pie a PI” event on Thursday, March 14. As the name suggests, this event involves gathering round and watching CAMB faculty members get pies thrown in their faces. In the days leading up to Pi Day, those wanting to pie a PI purchased $1 raffle tickets to enter for the chance...

July 10, 2019

For Dr. Michael Convente, a 2016 alum from DSRB, a professional move out of academia didn’t mean giving up on the scientific enterprise. After finishing his doctoral training in the Shore Lab, Michael began working as a medical writer for Scientific Pathways, a medical communications agency within the Nucleus Global network. His office is based in nearby Hamilton, NJ, so Michael is even able to stay local in Philadelphia, and makes the daily commute by train. Scientific Pathways may be relatively new on the scene, but it already has offices in the U.S. and the U.K., producing deliverable content and consulting on medical communications strategy for both a...

July 3, 2019

Dr. Rachel Leibman graduated from CAMB (Microbiology, Virology, and Parasitology) in 2017 after completing her training in Dr. Jim Riley’s laboratory. After two years in her current position as a Clinical Scientist, she is excited to share her experience with current students, and tell us how CAMB graduates are undoubtedly qualified for this translational-focused field.

Rachel works for Stemcentrx, an oncology biotech startup acquired by AbbVie, a global pharmaceutical company and spin-off of Abbott Laboratories. As a Clinical Scientist, she supports clinical trials and clinical program development. Rachel describes herself as the right-hand woman to the M...

February 19, 2019

Malaria remains one of the world’s most devastating diseases. Campaigns to eradicate transmission have yielded encouraging results in recent years. However, expansion of vector habitats has resulted in substantial increases in disease burden in the Americas, South-East Asia, and Africa, with over 2 million new cases and 445,000 deaths reported in 2016.

While Plasmodium falciparum is responsible for most malaria cases in Africa, Plasmodium vivax is the leading cause of malaria elsewhere in the world, particularly in Southeast Asia and South America. P. vivax is thought to have originated as a human pathogen by zoonoses of ape parasites; the long-standing do...

February 19, 2019

Little League. High School Sports. NCAA College Athletics. The Super Bowl. The Olympic Games. Athletics are an important pillar throughout all stages of society. The Eagles are playing on everyone’s TV on most Sundays of the school year. Yet, student athletes seem to be forgotten in graduate school. Many CAMB students are still highly involved in athletics, from the social intramural level up through the professional level. These students have a passion competing in athletics that their fellow students and PIs alike are unaware of. This article spotlights four graduate student athletes, or “GRAthletes,” who participate in in a variety of sports to compete...

February 19, 2019

The field of public health goes hand in hand with biomedical research to keep people healthy and safe through disease prevention. Doctoral students in Biomedical Graduate Studies (BGS) looking to form a bridge between their research and public health can do so through the Public Health Certificate Program (PHCP), which is offered through the Master of Public Health Program (MPH Program). Founded in 2006, PHCP complements graduate studies by teaching students population-based approaches to research that allow them to think broadly about the effect of biomedical research on public health.

Training biomedical scientists from a public health perspective is of...

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