Regenerating the lung: harnessing the untapped potential of AT2 cells

Where are they now – Theonie Anastassiadis

Faculty Spotlight: Will Bailis

Be The Match

GRAthletes in CAMB: Coral Kasden competes at 2019 Pan American Games in Lima, Peru

Greening Our Labs

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The CAMB Symposium helps strengthen the CAMB community by bringing together current and former students. Twenty-seven CAMB alumni, whose careers range from tenure track professors to patent judge, attended the symposium. They participated in career panels to share their post-graduation experiences, and give current students advice on how to navigate life after graduate school. Despite the varied career paths of the panelists, each panel discussed similar themes.

Many of the panelists commented on things they did, or wish they had done, during graduate school to help them while looking for jobs. Panelists stressed that networking is an extremely important s...

November 27, 2018

Since beginning graduate school, I have been a part of the Graduate Training in Medical Science (GTMS) Certificate Program. The GTMS program integrates focused medical education and experience into the doctoral curriculum, giving Ph.D. students insight into the integration of lab and clinic. Started in 2006 and funded by the Howard Hughes Medical Institute, the program was so successful that Penn decided to keep it going after the three-year pilot grant ended.

Directed by Dr. Hao Shen and Dr. Jonathan Katz, the rigorous program focuses on training basic scientists to have a clearer understanding of human biology and pathology through clinically relevant re...

November 27, 2018

As non-academic careers for biomedical scientists gain in popularity, certificate programs offer exciting opportunities to acquire academic and practical experience in diverse fields of study. One such program is the Certificate in Law. A subset of the Master in Law program offered by the University of Pennsylvania Law School, the certificate program allows students to expand their understanding of legal concepts and practices. Students receive their certification after successful completion of four courses at Penn Law, including the required foundational course “Introduction to U.S. Law and Legal Methods (LAWM 511).” At no extra cost to CAMB students, th...

November 27, 2018

Dr. Skye Geherin describes herself as a scientific translator. The CAMB (Microbiology, Virology, and Parasitology) 2014 alumna and former student of Dr. Gudrun Philomena Fiona Debes is the Associate Director of Scientific Communications and a Senior Medical Writer at the Vaniam Group, a virtual network of healthcare and communications agencies.

The Vaniam Group provides four services: strategic consulting, external expert engagement, insights gathering initiatives, and scientific communications. In essence, the agency partners with pharmaceutical companies or biotech devices to help them publish their data. Skye reviews the client’s raw data and translates...

November 27, 2018

When we consider the future of cancer treatment, chemotherapy pales in comparison to immunotherapy. Unlike chemotherapy, which stops or blocks rapidly growing cells and can lead to adverse side effects, immunotherapy modifies a patient’s own cells to enhance or restore the cancer-fighting ability of the immune system. Immunotherapy has led to a marked improvement in clinical outcomes, but unfortunately only a subset of patients respond positively to this treatment. It is well known that different tumors have diverse genetic and epigenetic alterations that contribute to the range of phenotypes, and ultimately the success of treatment. However, the field la...

August 25, 2018

After spending months or years designing, performing and polishing a research project, it seems unjust to distill it down to a few thousand word report describing a limited set of data visualizations. However, the ability to honestly and succinctly do so is a crucial skill for life science researchers. Additionally, in an era where there is a glut in the global supply of doctorates [1], how does one assess the quality of individuals earning that prestigious-sounding degree? Thus, it’s no surprise that the University of Pennsylvania’s Cellular and Molecular Biology (CAMB) graduate group stipulates that a doctoral candidate have a certain number of publicat...

August 25, 2018

With the constantly advancing technology landscape, it is now a necessity for researchers to evolve as well informed and trained technology architects. The Penn Center for Innovation (PCI) is Penn’s one-stop-shop for commercialization. PCI brings traditional technology transfer, corporate contracts, new venture creation and corporate alliance building together in a single matrix. To bolster their mission, PCI Fellowship program was started by PCI in 2008. The program aims at equipping graduate students and post-doctoral fellows with technical knowledge and practical experiences in technology transfer. On the tenth anniversary of this program, the CAMB Stu...

August 25, 2018

Stemming from a relatively recent explosion of research, the epigenetic regulation of gene expression is now appreciated as an important biological phenomenon. The prefix “epi-” means above or around in Greek, as epigenetics is defined by the study of DNA modifications that do not change the underlying sequence of the DNA. Importantly, these additions change cellular gene expression to diversify the functionality of cells with the same underlying genetic code.

Chemical modifications to DNA such as methyl groups (mCpG) are dynamically regulated to govern cell fate during development. The family of DNA methyltransferase enzymes, or DNMTs, covalently add mCp...

August 25, 2018

Dr. Melike Lakadamyali joined the Penn community in early 2017 after moving her lab from the Institute of Photonic Sciences in Barcelona to the Perelman School of Medicine. She is an assistant professor in the Department of Physiology, with a joint appointment in the Department of Cell and Developmental Biology. Dr. Lakadamyali is affiliated both with the Biochemistry and Molecular Biophysics and the Cell and Molecular Biology Graduate Groups.

Dr. Lakadamyali completed her Ph.D. in physics at Harvard University with Dr. Xiaowei Zhuang, whose lab developed super-resolution STORM microscopy. For her thesis work, Dr. Lakadamyali developed live-cell imaging te...

August 25, 2018

Every Friday morning, Helen C. Davies, a 93-year-old Professor of Microbiology at University of Pennsylvania Perelman School of Medicine, sets off punctually at 7:45 a.m. to the infectious disease management meeting at the Hospital of the University of Pennsylvania. Helen, who insists people call her by first name, can’t remember how long she has been attending these meetings.

“For a mighty long time,” according to her. But what she can remember is that she used to be able to walk freely to these meetings -then with a cane. Now, she wheels.

“How are you today, Helen?” greets a senior physician in the elevator concourse.

“I’m good, dear,” she replies, whil...

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